Fam120a | family with sequence similarity 120, member A

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Hearing/vestibular/ear Vision/eye Behavior/neurological Skeleton Cardiovascular system

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetFam120aem1(IMPC)JhomozygoteEarly adult1.62x10-5 
increased lean body mass2 supporting datasetsFam120aem1(IMPC)JhomozygoteEarly adult8.87x10-6 
hyperactivity4 supporting datasetsFam120aem1(IMPC)JhomozygoteEarly adult3.98x10-6 
decreased total body fat amount2 supporting datasetsFam120aem1(IMPC)JhomozygoteEarly adult9.78x10-6 
increased circulating alkaline phosphatase level1 supporting datasetFam120aem1(IMPC)JhomozygoteEarly adult1.08x10-5 
increased exploration in new environment1 supporting datasetFam120aem1(IMPC)JhomozygoteEarly adult2.81x10-6 
increased heart weight1 supporting datasetFam120aem1(IMPC)JhomozygoteEarly adult8x10-10 
increased bone mineral content1 supporting datasetFam120aem1(IMPC)JhomozygoteEarly adult4.1x10-6 
increased bone mineral density1 supporting datasetFam120aem1(IMPC)JhomozygoteEarly adult1.95x10-5 
abnormal auditory brainstem response1 supporting datasetFam120aem1(IMPC)JhomozygoteEarly adult9.09x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam120aem1(IMPC)JExon Deletionmouse

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