Zfc3h1 | zinc finger, C3H1-type containing

GeneMGI:2446143Synonyms: Psrc2, Ccdc131

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Embryo Growth/size/body region Vision/eye Liver/biliary system Mortality/aging Cardiovascular system

15 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsZfc3h1em1(IMPC)MbphomozygoteEarly adultN/A * 
small liver1 supporting datasetZfc3h1em1(IMPC)MbpheterozygoteEarly adultN/A * 
embryonic growth retardation1 supporting datasetZfc3h1em1(IMPC)MbphomozygoteE9.5N/A * 
abnormal liver morphology1 supporting datasetZfc3h1em1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal retina vasculature morphology1 supporting datasetZfc3h1em1(IMPC)MbpheterozygoteEarly adult1.72x10-5 
persistence of hyaloid vascular system1 supporting datasetZfc3h1em1(IMPC)MbpheterozygoteEarly adult3.68x10-5 
increased body length1 supporting datasetZfc3h1em1(IMPC)MbpheterozygoteEarly adult1.09x10-45 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfc3h1em1(IMPC)MbpExon Deletionmouse
Zfc3h1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Zfc3h1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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