Arrdc1 | arrestin domain containing 1

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye

15 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

increased circulating alanine transaminase level1 supporting datasetArrdc1tm1.1(KOMP)VlcghomozygoteEarly adult8.41x10-8 
increased fasting circulating glucose level1 supporting datasetArrdc1tm1.1(KOMP)VlcgheterozygoteEarly adult9.22x10-5 
abnormal lens morphology1 supporting datasetArrdc1tm1.1(KOMP)VlcghomozygoteEarly adult5.31x10-5 
abnormal retina morphology1 supporting datasetArrdc1tm1.1(KOMP)VlcgheterozygoteEarly adult4.28x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arrdc1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Arrdc1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Arrdc1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Arrdc1tm45558(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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