Nemp1 | nuclear envelope integral membrane protein 1

GeneMGI:2446113Synonyms: Tmem194

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



female infertility	1 supporting dataset	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased locomotor activity	1 supporting dataset	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	7.01x10^-5
decreased mean corpuscular volume	1 supporting dataset	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	2.01x10^-37
abnormal eye morphology	1 supporting dataset	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	2 supporting datasets	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased spleen weight	1 supporting dataset	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	3.62x10^-24
small testis	1 supporting dataset	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	1.99x10^-28
abnormal testis morphology	1 supporting dataset	Nemp1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nemp1.

Associated images

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Histopathology

There is no histopathology data found for Nemp1.

IMPC related publications

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External links

No external links available for Nemp1.

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*Nemp1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Nemp1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nemp1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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