Hace1 | HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1

GeneMGI:2446110Synonyms: A730034A22Rik, 1700042J16Rik

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:46Adult tissues

21Embryo tissues

Phenotypes

Life Stage:



preweaning lethality, incomplete penetrance	1 supporting dataset	Hace1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Hace1^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hace1.

Associated images

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Histopathology

There is no histopathology data found for Hace1.

IMPC related publications

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External links

No external links available for Hace1.

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*Hace1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hace1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hace1^{tm1c(KOMP)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse

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