Flnb | filamin, beta
GeneMGI:2446089
Physiological systems
17 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton Mortality/aging
10 No significant impact
7 Not tested
Gene metrics:8Significant phenotypes
10Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| increased circulating serum albumin level | 1 supporting dataset | Flnbtm1b(KOMP)Wtsi | heterozygote | Early adult | 3.27x10-5 | ||
| decreased bone mineral content | 2 supporting datasets | Flnbtm1b(KOMP)Wtsi | heterozygote | Early adult | 2.68x10-6 | ||
| decreased neutrophil cell number | 1 supporting dataset | Flnbtm1b(KOMP)Wtsi | heterozygote | Early adult | 9.28x10-7 | ||
| decreased lean body mass | 2 supporting datasets | Flnbtm1b(KOMP)Wtsi | heterozygote | Early adult | 3.9x10-10 | ||
| decreased bone mineral density | 1 supporting dataset | Flnbtm1b(KOMP)Wtsi | heterozygote | Early adult | 8.15x10-6 | ||
| increased total body fat amount | 2 supporting datasets | Flnbtm1b(KOMP)Wtsi | heterozygote | Early adult | 7.81x10-6 | ||
| decreased red blood cell distribution width | 1 supporting dataset | Flnbtm1b(KOMP)Wtsi | heterozygote | Early adult | 7.49x10-8 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Flnbtm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Flnb.
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| Flnbtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Flnbtm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Flnbtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |