Rfx6 | regulatory factor X, 6

GeneMGI:2445208Synonyms: 4930572O07Rik, Rfxdc1

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

20 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

30Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Rfx6^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
impaired glucose tolerance	1 supporting dataset	Rfx6^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	7.95x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rfx6.

Associated images

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Histopathology

There is no histopathology data found for Rfx6.

IMPC related publications

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External links

No external links available for Rfx6.

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*Rfx6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Rfx6^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Rfx6^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rfx6^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Rfx6^{tm43096(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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