Tmem184b | transmembrane protein 184b

GeneMGI:2445179Synonyms: 4732495E13Rik

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Behavior/neurological Mortality/aging

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	5 supporting datasets	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.14x10^-14
abnormal lymph node morphology	1 supporting dataset	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased vertical activity	1 supporting dataset	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.44x10^-7
small testis	1 supporting dataset	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	2 supporting datasets	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased thigmotaxis	2 supporting datasets	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.45x10^-8
abnormal behavior	1 supporting dataset	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.46x10^-8
abnormal testis morphology	1 supporting dataset	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Tmem184b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	8.21x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem184b.

Associated images

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Histopathology

There is no histopathology data found for Tmem184b.

IMPC related publications

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External links

No external links available for Tmem184b.

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*Tmem184b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Tmem184b^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Tmem184b^{tm208822(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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