Dync2i1 | dynein 2 intermediate chain 1
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Embryo Growth/size/body region Digestive/alimentary Mortality/aging Cardiovascular system Renal/urinary system
15 No significant impact
3 Not tested
Data collections
Gene metrics:8Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic growth retardation | 1 supporting dataset | Dync2i1em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Dync2i1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged urinary bladder | 1 supporting dataset | Dync2i1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Dync2i1em1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| abnormal stomach morphology | 1 supporting dataset | Dync2i1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Dync2i1em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Dync2i1em1(IMPC)Tcp | homozygote | E12.5 | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Dync2i1em1(IMPC)Tcp | homozygote | E9.5 | N/A * |
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External links
No external links available for Dync2i1.
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| Dync2i1em1(IMPC)Tcp | Exon Deletion | | mouse |
| Dync2i1tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Dync2i1tm3a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |