Hmbox1 | homeobox containing 1

GeneMGI:2445066Synonyms: F830020C16Rik

Physiological systems

18 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

9 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular hemoglobin	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	5.86x10^-5
abnormal sternum morphology	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal lens morphology	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	7.78x10^-5
thick skin	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased circulating chloride level	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	1.35x10^-5
enlarged kidney	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
tremors	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	9.17x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	1.33x10^-5
decreased lymphocyte cell number	1 supporting dataset	Hmbox1^em1(IMPC)Tcp	homozygote	Early adult	9.28x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hmbox1.

Associated images

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Histopathology

There is no histopathology data found for Hmbox1.

IMPC related publications

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External links

No external links available for Hmbox1.

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*Hmbox1^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Hmbox1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Hmbox1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Hmbox1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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