Spg11 | SPG11, spatacsin vesicle trafficking associated
Physiological systems
17 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Adipose tissue Hematopoietic system Behavior/neurological Cardiovascular system
11 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating total protein level | 1 supporting dataset | Spg11em1(IMPC)J | homozygote | Early adult | 1.23x10-5 | ||
| increased leukocyte cell number | 1 supporting dataset | Spg11em1(IMPC)J | homozygote | Early adult | 2.02x10-5 | ||
| increased total body fat amount | 1 supporting dataset | Spg11em1(IMPC)J | homozygote | Early adult | 6.99x10-5 | ||
| increased startle reflex | 1 supporting dataset | Spg11em1(IMPC)J | homozygote | Early adult | 8.66x10-8 | ||
| decreased exploration in new environment | 1 supporting dataset | Spg11em1(IMPC)J | homozygote | Early adult | 4.3x10-5 | ||
| prolonged RR interval | 1 supporting dataset | Spg11em1(IMPC)J | homozygote | Early adult | 9.77x10-6 |
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External links
No external links available for Spg11.
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| Spg11em1(IMPC)J | Exon Deletion | | mouse |