Mical2 | microtubule associated monooxygenase, calponin and LIM domain containing 2

GeneMGI:2444947Synonyms: 4921517J23Rik, 5330438E18Rik, +2 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Nervous system Vision/eye Cardiovascular system Renal/urinary system

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal ovary morphology	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
small heart	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
small kidney	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
microphthalmia	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased lean body mass	2 supporting datasets	Mical2^em1(IMPC)Tcp	homozygote	Late adult	3.64x10^-6
decreased prepulse inhibition	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Early adult	7.57x10^-6
enlarged uterus	1 supporting dataset	Mical2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mical2.

Associated images

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Histopathology

There is no histopathology data found for Mical2.

IMPC related publications

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External links

No external links available for Mical2.

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*Mical2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Mical2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mical2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mical2^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mical2^{tm42371(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Mical2^{tm42371(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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