Efr3b | EFR3 homolog B

GeneMGI:2444851Synonyms: C030014M07Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Nervous system Behavior/neurological Skeleton

13 No significant impact

4 Not tested

Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity5 supporting datasetsEfr3bem1(IMPC)MbphomozygoteEarly adult3.43x10-39 
decreased total body fat amount1 supporting datasetEfr3bem1(IMPC)MbphomozygoteEarly adult1.98x10-6 
increased bone mineral content1 supporting datasetEfr3bem1(IMPC)MbphomozygoteEarly adult4.99x10-6 
increased grip strength2 supporting datasetsEfr3bem1(IMPC)MbphomozygoteEarly adult6.49x10-7 
increased thigmotaxis2 supporting datasetsEfr3bem1(IMPC)MbphomozygoteEarly adult1.16x10-5 
decreased circulating creatinine level1 supporting datasetEfr3bem1(IMPC)MbphomozygoteEarly adult2.96x10-7 
impaired glucose tolerance1 supporting datasetEfr3bem1(IMPC)MbphomozygoteEarly adult4.27x10-5 
decreased prepulse inhibition3 supporting datasetsEfr3bem1(IMPC)MbphomozygoteEarly adult7.25x10-7 
decreased locomotor activity2 supporting datasetsEfr3bem1(IMPC)MbphomozygoteEarly adult2.64x10-5 
female infertility1 supporting datasetEfr3bem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Efr3bem1(IMPC)MbpExon Deletionmouse
Efr3btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Efr3btm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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