Hhat | hedgehog acyltransferase

GeneMGI:2444681Synonyms: 2810432O22Rik, Skn

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Mortality/aging

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetHhatem1(IMPC)CcpczheterozygoteEarly adultN/A * 
increased memory-marker CD4-positive NK T cell number1 supporting datasetHhatem1(IMPC)CcpczheterozygoteEarly adult4.57x10-6 
preweaning lethality, complete penetrance1 supporting datasetHhatem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetHhatem1(IMPC)CcpczheterozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetHhatem1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetHhatem1(IMPC)CcpczheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hhatem1(IMPC)CcpczExon Deletionmouse

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