Susd6 | sushi domain containing 6

GeneMGI:2444661Synonyms: 4933426M11Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased circulating alanine transaminase level	1 supporting dataset	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	1.31x10^-14
increased lymphocyte cell number	2 supporting datasets	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	1.34x10^-6
decreased circulating HDL cholesterol level	1 supporting dataset	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	3.67x10^-5
increased circulating bilirubin level	1 supporting dataset	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	1.01x10^-5
decreased circulating fructosamine level	1 supporting dataset	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	3.45x10^-5
enlarged spleen	1 supporting dataset	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	N/A ^*
decreased neutrophil cell number	1 supporting dataset	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	5.73x10^-5
decreased monocyte cell number	2 supporting datasets	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	5.72x10^-11
increased startle reflex	1 supporting dataset	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.73x10^-8
decreased total body fat amount	1 supporting dataset	Susd6^{tm1b(KOMP)Wtsi}	homozygote	Late adult	7.55x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Susd6.

Associated images

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Histopathology

There is no histopathology data found for Susd6.

IMPC related publications

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External links

No external links available for Susd6.

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*Susd6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Susd6^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Susd6^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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