Hpdl | 4-hydroxyphenylpyruvate dioxygenase-like
Physiological systems
22 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Integument Embryo Growth/size/body region Nervous system Vision/eye Behavior/neurological Cardiovascular system Mortality/aging
14 No significant impact
2 Not tested
Data collections
Gene metrics:16Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased body length | 1 supporting dataset | Hpdlem1(IMPC)Mbp | heterozygote | Early adult | 5.6x10-5 | ||
abnormal vitreous body morphology | 1 supporting dataset | Hpdlem1(IMPC)Mbp | heterozygote | Early adult | 3.17x10-5 | ||
decreased thigmotaxis | 2 supporting datasets | Hpdlem1(IMPC)Mbp | heterozygote | Early adult | 6.09x10-5 | ||
decreased prepulse inhibition | 1 supporting dataset | Hpdlem1(IMPC)Mbp | heterozygote | Early adult | 6.71x10-5 | ||
no spontaneous movement | 1 supporting dataset | Hpdlem1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
enlarged heart | 1 supporting dataset | Hpdlem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
decreased anxiety-related response | 1 supporting dataset | Hpdlem1(IMPC)Mbp | heterozygote | Early adult | 8.09x10-6 | ||
preweaning lethality, incomplete penetrance | 3 supporting datasets | Hpdlem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal skin morphology | 1 supporting dataset | Hpdlem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
abnormal retina morphology | 1 supporting dataset | Hpdlem1(IMPC)Mbp | heterozygote | Early adult | 7.23x10-5 |
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External links
No external links available for Hpdl.
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