Bltp1 | bridge-like lipid transfer protein family member 1

GeneMGI:2444631Synonyms: Tweek, FSA, +1 more

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Embryo Growth/size/body region Vision/eye Behavior/neurological Mortality/aging Cardiovascular system

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

2Associated diseases

Expression examined in:49Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



cataract	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.94x10^-5
increased startle reflex	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.81x10^-6
embryonic growth retardation	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	2 supporting datasets	Bltp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal lens morphology	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.05x10^-7
increased circulating glucose level	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.13x10^-5
impaired glucose tolerance	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.95x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.56x10^-5
abnormal retina vasculature morphology	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.13x10^-5
hemorrhage	1 supporting dataset	Bltp1^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bltp1.

Associated images

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Histopathology

There is no histopathology data found for Bltp1.

IMPC related publications

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External links

No external links available for Bltp1.

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*Bltp1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Bltp1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Bltp1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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