Kmt5b | lysine methyltransferase 5B
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Behavior/neurological Mortality/aging
16 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| decreased body weight | 4 supporting datasets | Kmt5btm1a(KOMP)Wtsi | heterozygote | Early adult | 1.84x10-7 | ||
| decreased body weight | 4 supporting datasets | Kmt5btm1a(KOMP)Wtsi | homozygote | Early adult | 1.24x10-11 | ||
| abnormal tail movements | 1 supporting dataset | Kmt5btm1a(KOMP)Wtsi | heterozygote | Early adult | 7.74x10-6 | ||
| increased thermal nociceptive threshold | 1 supporting dataset | Kmt5btm1a(KOMP)Wtsi | heterozygote | Early adult | 1.88x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Kmt5btm1a(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased circulating chloride level | 1 supporting dataset | Kmt5btm1a(KOMP)Wtsi | homozygote | Early adult | 4.17x10-5 |
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External links
No external links available for Kmt5b.
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| Kmt5btm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Kmt5btm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |
| Kmt5btm2e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |
| Kmt5btm39901(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Kmt5btm39901(L1L2_st2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |