Mapkap1 | mitogen-activated protein kinase associated protein 1
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Vision/eye Mortality/aging Cardiovascular system
17 No significant impact
2 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues
| decreased total retina thickness | 1 supporting dataset | Mapkap1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.12x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Mapkap1tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Mapkap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Mapkap1tm1b(EUCOMM)Wtsi | homozygote | E15.5 | N/A * | ||
| increased cornea thickness | 1 supporting dataset | Mapkap1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.57x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Mapkap1tm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| dilated heart left ventricle | 2 supporting datasets | Mapkap1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 4.62x10-5 |
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External links
No external links available for Mapkap1.
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| Mapkap1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Mapkap1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Mapkap1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |