Fitm2 | fat storage-inducing transmembrane protein 2

GeneMGI:2444508Synonyms: D930001I22Rik, Fit2

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Embryo Growth/size/body region Nervous system Mortality/aging Cardiovascular system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



prenatal lethality prior to heart atrial septation	1 supporting dataset	Fitm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
decreased prepulse inhibition	1 supporting dataset	Fitm2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.81x10^-6
abnormal pericardium morphology	1 supporting dataset	Fitm2^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Fitm2^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Fitm2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fitm2.

Associated images

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Histopathology

There is no histopathology data found for Fitm2.

IMPC related publications

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External links

No external links available for Fitm2.

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*Fitm2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Fitm2^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Fitm2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes