Dnai7 | dynein axonemal intermediate chain 7

GeneMGI:2444480Synonyms: Casc1, Las1, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Vision/eye Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



persistence of hyaloid vascular system	1 supporting dataset	Dnai7^em1(IMPC)Tcp	homozygote	Early adult	4.58x10^-5
male infertility	1 supporting dataset	Dnai7^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal retina vasculature morphology	1 supporting dataset	Dnai7^em1(IMPC)Tcp	homozygote	Early adult	2.42x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Dnai7^em1(IMPC)Tcp	homozygote	Early adult	1.94x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dnai7.

Associated images

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Histopathology

There is no histopathology data found for Dnai7.

IMPC related publications

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External links

No external links available for Dnai7.

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*Dnai7^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Dnai7^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dnai7^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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