Arhgef10 | Rho guanine nucleotide exchange factor 10

GeneMGI:2444453Synonyms: 6430549H08Rik

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes



decreased circulating glucose level	1 supporting dataset	Arhgef10^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.43x10^-6
increased circulating potassium level	1 supporting dataset	Arhgef10^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.38x10^-6
increased circulating alanine transaminase level	1 supporting dataset	Arhgef10^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.61x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arhgef10.

Associated images

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Histopathology

There is no histopathology data found for Arhgef10.

IMPC related publications

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External links

No external links available for Arhgef10.

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*Arhgef10^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Arhgef10^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Arhgef10^{tm94296(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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