Rab11fip3 | RAB11 family interacting protein 3 (class II)

GeneMGI:2444431Synonyms: D030060O14Rik, Rab11-FIP3

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response5 supporting datasetsRab11fip3em1(IMPC)JhomozygoteEarly adult6.54x10-13 
increased vertical activity1 supporting datasetRab11fip3em1(IMPC)JhomozygoteEarly adult9.75x10-8 
decreased thigmotaxis2 supporting datasetsRab11fip3em1(IMPC)JhomozygoteEarly adult2.81x10-7 
improved glucose tolerance1 supporting datasetRab11fip3em1(IMPC)JhomozygoteEarly adult8.44x10-6 
abnormal startle reflex1 supporting datasetRab11fip3em1(IMPC)JhomozygoteEarly adult2.73x10-8 
decreased startle reflex1 supporting datasetRab11fip3em1(IMPC)JhomozygoteEarly adult6.82x10-9 
abnormal behavior1 supporting datasetRab11fip3em1(IMPC)JhomozygoteEarly adult2.82x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rab11fip3em1(IMPC)JExon Deletionmouse
Rab11fip3tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rab11fip3tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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