Snrnp200 | small nuclear ribonucleoprotein 200 (U5)

GeneMGI:2444401Synonyms: Ascc3l1, HELIC2, +2 more

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

21Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



exophthalmos	1 supporting dataset	Snrnp200^{tm1b(KOMP)Mbp}	heterozygote	Early adult	9.52x10^-6
impaired pupillary reflex	1 supporting dataset	Snrnp200^{tm1b(KOMP)Mbp}	heterozygote	Early adult	8.53x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Snrnp200^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*
increased monocyte cell number	1 supporting dataset	Snrnp200^{tm1b(KOMP)Mbp}	heterozygote	Early adult	3.64x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Snrnp200^{tm1b(KOMP)Mbp}	homozygote	E9.5	N/A ^*
enlarged heart	1 supporting dataset	Snrnp200^{tm1b(KOMP)Mbp}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Snrnp200.

Associated images

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Histopathology

There is no histopathology data found for Snrnp200.

IMPC related publications

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External links

No external links available for Snrnp200.

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*Snrnp200^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Snrnp200^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Snrnp200^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	es cell

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