Ube2o | ubiquitin-conjugating enzyme E2O
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging
14 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Ube2otm1.1(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Ube2otm1.1(KOMP)Mbp | heterozygote | Early adult | 3.99x10-12 | ||
| increased grip strength | 1 supporting dataset | Ube2otm1.1(KOMP)Mbp | heterozygote | Early adult | 3.73x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Ube2otm1.1(KOMP)Mbp | heterozygote | Early adult | 5.96x10-5 |
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External links
No external links available for Ube2o.
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| Ube2otm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Ube2otm1.1(KOMP)Mbp | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Ube2otm106068(L1L2_Pgk_P) | Reporter-tagged deletion allele (with selection cassette) | | targeting vector |
| Ube2otm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ube2otm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |