Gcn1 | GCN1 activator of EIF2AK4

GeneMGI:2444248Synonyms: GCN1L, G431004K08Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating glucose level	1 supporting dataset	Gcn1^em1(IMPC)J	heterozygote	Early adult	1.6x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Gcn1^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased circulating bilirubin level	1 supporting dataset	Gcn1^em1(IMPC)J	heterozygote	Early adult	5.52x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gcn1.

Associated images

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Histopathology

There is no histopathology data found for Gcn1.

IMPC related publications

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External links

No external links available for Gcn1.

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*Gcn1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Gcn1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Gcn1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gcn1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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