Vps13c | vacuolar protein sorting 13C

GeneMGI:2444207Synonyms: C230055H22Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased locomotor activity	6 supporting datasets	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	2.48x10^-8
increased circulating lipase level	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.2x10^-22
increased circulating aspartate transaminase level	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	2.15x10^-6
increased red blood cell distribution width	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.6x10^-7
abnormal behavior	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	4.09x10^-7
decreased hematocrit	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.06x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.94x10^-6
decreased circulating fructosamine level	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	1.89x10^-10
increased circulating amylase level	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.56x10^-28
increased circulating alanine transaminase level	1 supporting dataset	Vps13c^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	8.7x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Vps13c.

Associated images

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Histopathology

There is no histopathology data found for Vps13c.

IMPC related publications

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External links

No external links available for Vps13c.

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*Vps13c^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Vps13c^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Vps13c^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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