Rasal3 | RAS protein activator like 3

GeneMGI:2444128Synonyms: A430107D22Rik

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Skeleton

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal eye anterior chamber depth	1 supporting dataset	Rasal3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.28x10^-5
increased circulating triglyceride level	1 supporting dataset	Rasal3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.97x10^-5
increased circulating cholesterol level	1 supporting dataset	Rasal3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.97x10^-6
decreased lymphocyte cell number	1 supporting dataset	Rasal3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.31x10^-9
short tibia	2 supporting datasets	Rasal3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.91x10^-8
decreased circulating creatinine level	1 supporting dataset	Rasal3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.75x10^-5
decreased body length	1 supporting dataset	Rasal3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.56x10^-5
increased eosinophil cell number	1 supporting dataset	Rasal3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.2x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rasal3.

Associated images

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Histopathology

There is no histopathology data found for Rasal3.

IMPC related publications

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External links

No external links available for Rasal3.

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*Rasal3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rasal3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rasal3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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