Tanc2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

GeneMGI:2444121Synonyms: 3526402J09Rik, 5730590C14Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Nervous system Behavior/neurological Skeleton

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased exploration in new environment	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.15x10^-5
abnormal locomotor behavior	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	8.69x10^-6
decreased anxiety-related response	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	4.82x10^-5
short tibia	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.51x10^-5
hyperactivity	5 supporting datasets	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	9.47x10^-8
abnormal behavior	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	4.92x10^-5
increased grip strength	2 supporting datasets	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	5.99x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.85x10^-5
decreased respiratory quotient	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	8.49x10^-5
decreased circulating total protein level	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	4.41x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tanc2.

Associated images

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Histopathology

There is no histopathology data found for Tanc2.

IMPC related publications

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External links

No external links available for Tanc2.

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*Tanc2^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Tanc2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Tanc2^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Tanc2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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