Tanc2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

GeneMGI:2444121Synonyms: 3526402J09Rik, 5730590C14Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Nervous system Behavior/neurological Skeleton

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased exploration in new environment	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.15x10^-5
abnormal locomotor behavior	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	8.69x10^-6
decreased anxiety-related response	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	4.82x10^-5
short tibia	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.51x10^-5
hyperactivity	5 supporting datasets	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	9.47x10^-8
abnormal behavior	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	4.92x10^-5
increased grip strength	2 supporting datasets	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	5.99x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.85x10^-5
decreased respiratory quotient	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	8.49x10^-5
decreased circulating total protein level	1 supporting dataset	Tanc2^{em1(IMPC)Hmgu}	homozygote	Early adult	4.41x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Tanc2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Tanc2.

IMPC related publications

Loading...

External links

No external links available for Tanc2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Tanc2^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Tanc2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Tanc2^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tanc2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes