Hecw1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
17 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| increased circulating phosphate level | 1 supporting dataset | Hecw1tm2b(EUCOMM)Hmgu | homozygote | Late adult | 1.06x10-5 | ||
| impaired righting response | 1 supporting dataset | Hecw1tm2b(EUCOMM)Hmgu | homozygote | Middle aged adult | 3.82x10-7 | ||
| decreased exploration in new environment | 1 supporting dataset | Hecw1tm2b(EUCOMM)Hmgu | homozygote | Middle aged adult | 1.48x10-6 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Hecw1tm2b(EUCOMM)Hmgu | homozygote | Early adult | 2.13x10-5 | ||
| limb grasping | 1 supporting dataset | Hecw1tm2b(EUCOMM)Hmgu | homozygote | Early adult | 1.02x10-7 | ||
| tremors | 1 supporting dataset | Hecw1tm2b(EUCOMM)Hmgu | homozygote | Early adult | 2.6x10-5 |
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External links
No external links available for Hecw1.
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| Hecw1tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Hecw1tm2b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Hecw1tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |