Dpp9 | dipeptidylpeptidase 9

GeneMGI:2443967Synonyms: 6430584G11Rik, DPRP2

Physiological systems

24 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

17 No significant impact

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

2Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Dpp9^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased thigmotaxis	2 supporting datasets	Dpp9^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.85x10^-6
abnormal lens morphology	1 supporting dataset	Dpp9^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.91x10^-5
increased anxiety-related response	1 supporting dataset	Dpp9^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.61x10^-5
increased circulating iron level	1 supporting dataset	Dpp9^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.42x10^-5
decreased lean body mass	1 supporting dataset	Dpp9^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.11x10^-6
abnormal behavior	1 supporting dataset	Dpp9^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	6.62x10^-16
decreased circulating phosphate level	1 supporting dataset	Dpp9^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	1.27x10^-6
tremors	1 supporting dataset	Dpp9^{em1(IMPC)Ccpcz}	heterozygote	Early adult	7.69x10^-5
abnormal behavior	1 supporting dataset	Dpp9^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.85x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dpp9.

Associated images

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Histopathology

There is no histopathology data found for Dpp9.

IMPC related publications

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External links

No external links available for Dpp9.

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*Dpp9^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Dpp9^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Dpp9^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dpp9^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dpp9^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dpp9^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Dpp9^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Dpp9^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dpp9^{tm3e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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