Cadps2 | Ca2+-dependent activator protein for secretion 2

GeneMGI:2443963Synonyms: Caps2, A230044C21Rik, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Endocrine/exocrine gland Digestive/alimentary

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal circulating alkaline phosphatase level1 supporting datasetCadps2em1(IMPC)RbrchomozygoteLate adult1.5x10-5 
enlarged lymph nodes2 supporting datasetsCadps2em1(IMPC)RbrchomozygoteLate adultN/A * 
abnormal salivary gland morphology2 supporting datasetsCadps2em1(IMPC)RbrchomozygoteLate adultN/A * 
abnormal pancreas morphology2 supporting datasetsCadps2em1(IMPC)RbrchomozygoteLate adultN/A * 
abnormal pancreas morphology2 supporting datasetsCadps2em1(IMPC)RbrchomozygoteEarly adultN/A * 
abnormal lymph node morphology2 supporting datasetsCadps2em1(IMPC)RbrchomozygoteLate adultN/A * 
abnormal duodenum morphology1 supporting datasetCadps2em1(IMPC)RbrchomozygoteLate adultN/A * 
abnormal ileum morphology1 supporting datasetCadps2em1(IMPC)RbrchomozygoteLate adultN/A * 
abnormal jejunum morphology1 supporting datasetCadps2em1(IMPC)RbrchomozygoteLate adultN/A * 
increased circulating amylase level1 supporting datasetCadps2em1(IMPC)RbrchomozygoteEarly adult8.54x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cadps2em1(IMPC)RbrcExon Deletionmouse
Cadps2em2(IMPC)RbrcExon Deletionmouse
Cadps2tm368660(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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