Dpy19l3 | dpy-19 like C-mannosyltransferase 3

GeneMGI:2443952Synonyms: 9330164H19Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased hematocrit1 supporting datasetDpy19l3tm1a(EUCOMM)WtsihomozygoteEarly adult5.61x10-5 
decreased hemoglobin content1 supporting datasetDpy19l3tm1a(EUCOMM)WtsihomozygoteEarly adult3.2x10-6 
thrombocytosis1 supporting datasetDpy19l3tm1a(EUCOMM)WtsihomozygoteEarly adult4.57x10-6 
decreased erythrocyte cell number1 supporting datasetDpy19l3tm1a(EUCOMM)WtsihomozygoteEarly adult3.78x10-5 
decreased circulating free fatty acids level1 supporting datasetDpy19l3tm1a(EUCOMM)WtsihomozygoteEarly adult5.71x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dpy19l3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dpy19l3tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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