Lypd6 | LY6/PLAUR domain containing 6

GeneMGI:2443848Synonyms: E130115E03Rik

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Integument Endocrine/exocrine gland Nervous system Mortality/aging

16 No significant impact

3 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetLypd6tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
small testis1 supporting datasetLypd6tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
small superior vagus ganglion1 supporting datasetLypd6tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetLypd6tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsLypd6tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
scaly skin1 supporting datasetLypd6tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
hydrometra1 supporting datasetLypd6tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
thick skin1 supporting datasetLypd6tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lypd6tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lypd6tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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