Snx8 | sorting nexin 8

GeneMGI:2443816Synonyms: B130023O14Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating serum albumin level	1 supporting dataset	Snx8^{tm2a(EUCOMM)Hmgu}	homozygote	Early adult	1.89x10^-9
decreased circulating total protein level	1 supporting dataset	Snx8^{tm2a(EUCOMM)Hmgu}	homozygote	Early adult	1.27x10^-5
decreased circulating fructosamine level	1 supporting dataset	Snx8^{tm2a(EUCOMM)Hmgu}	homozygote	Early adult	2.44x10^-10
increased circulating cholesterol level	1 supporting dataset	Snx8^{tm2a(EUCOMM)Hmgu}	homozygote	Early adult	2.16x10^-5
decreased circulating alkaline phosphatase level	1 supporting dataset	Snx8^{tm2a(EUCOMM)Hmgu}	homozygote	Early adult	2.94x10^-5
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Snx8^{tm2a(EUCOMM)Hmgu}	homozygote	Early adult	2.49x10^-5
increased circulating LDL cholesterol level	1 supporting dataset	Snx8^{tm2a(EUCOMM)Hmgu}	homozygote	Early adult	7.05x10^-6
increased leukocyte cell number	1 supporting dataset	Snx8^{tm2a(EUCOMM)Hmgu}	homozygote	Early adult	4.2x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Snx8.

Associated images

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Histopathology

There is no histopathology data found for Snx8.

IMPC related publications

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External links

No external links available for Snx8.

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*Snx8^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Snx8^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Snx8^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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