6430548M08Rik | RIKEN cDNA 6430548M08 gene

GeneMGI:2443793

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged lymph nodes	2 supporting datasets	6430548M08Rik^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	6430548M08Rik^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	6430548M08Rik^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	6430548M08Rik^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased circulating alkaline phosphatase level	1 supporting dataset	6430548M08Rik^em1(IMPC)Mbp	homozygote	Early adult	4.55x10^-7
increased circulating calcium level	1 supporting dataset	6430548M08Rik^em1(IMPC)Mbp	homozygote	Early adult	4.6x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for 6430548M08Rik.

Associated images

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Histopathology

There is no histopathology data found for 6430548M08Rik.

IMPC related publications

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External links

No external links available for 6430548M08Rik.

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*6430548M08Rik^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*6430548M08Rik^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*6430548M08Rik^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*6430548M08Rik^{tm42359(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*6430548M08Rik^{tm42359(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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