Large2 | LARGE xylosyl- and glucuronyltransferase 2

GeneMGI:2443769Synonyms: Gyltl1b, 5730485C17Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Cardiovascular system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina vasculature morphology	1 supporting dataset	Large2^em1(IMPC)Bay	homozygote	Early adult	4.1x10^-6
decreased total retina thickness	1 supporting dataset	Large2^em1(IMPC)Bay	homozygote	Early adult	7.38x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Large2.

Associated images

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Histopathology

There is no histopathology data found for Large2.

IMPC related publications

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External links

No external links available for Large2.

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*Large2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Large2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Large2^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Large2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Large2^{tm431865(L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes