Arhgap25 | Rho GTPase activating protein 25

GeneMGI:2443687Synonyms: A130039I20Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Vision/eye Hematopoietic system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	2 supporting datasets	Arhgap25^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.08x10^-6
abnormal retina pigmentation	2 supporting datasets	Arhgap25^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.67x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Arhgap25^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.51x10^-11
abnormal eye morphology	1 supporting dataset	Arhgap25^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.42x10^-7
thrombocytosis	1 supporting dataset	Arhgap25^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.03x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arhgap25.

Associated images

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Histopathology

There is no histopathology data found for Arhgap25.

IMPC related publications

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External links

No external links available for Arhgap25.

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*Arhgap25^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Arhgap25^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Arhgap25^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Arhgap25^{tm41908(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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