Marchf3 | membrane associated ring-CH-type finger 3

GeneMGI:2443667Synonyms: A530081L18Rik, 6330411I15Rik, +1 more

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

11 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:78Adult tissues

27Embryo tissues

Phenotypes

Phy. System:



abnormal kidney morphology	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
enlarged uterus	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
enhanced contextual conditioning behavior	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.45x10^-5
enlarged spleen	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased fasting circulating glucose level	1 supporting dataset	Marchf3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.24x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Marchf3.

Associated images

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Histopathology

There is no histopathology data found for Marchf3.

IMPC related publications

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External links

No external links available for Marchf3.

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*Marchf3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Marchf3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Marchf3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Marchf3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Marchf3^{tm33630(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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