Skor1 | SKI family transcriptional corepressor 1

GeneMGI:2443473Synonyms: Lbxcor1, Corl1, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating glucose level1 supporting datasetSkor1em1(IMPC)JheterozygoteEarly adult5.95x10-5 
preweaning lethality, complete penetrance1 supporting datasetSkor1em1(IMPC)JhomozygoteEarly adultN/A * 
decreased circulating bilirubin level1 supporting datasetSkor1em1(IMPC)JheterozygoteEarly adult9.73x10-9 
decreased circulating phosphate level1 supporting datasetSkor1em1(IMPC)JheterozygoteEarly adult3.08x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Skor1em1(IMPC)JExon Deletionmouse
Skor1tm209487(L1L2_Pgk_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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