Dse | dermatan sulfate epimerase

GeneMGI:2443455Synonyms: DS-epi1, B130024B19Rik, +1 more

Physiological systems

14 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

12 No significant impact

10 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues

Phenotypes

increased circulating aspartate transaminase level1 supporting datasetDsetm1b(EUCOMM)HmguheterozygoteEarly adult3.35x10-7 
preweaning lethality, complete penetrance1 supporting datasetDsetm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dsetm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Dsetm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Dsetm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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