Foxj3 | forkhead box J3

GeneMGI:2443432Synonyms: Fhd6, C330039G02Rik

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Adipose tissue Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Mortality/aging

12 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



abnormal sinus arrhythmia	1 supporting dataset	Foxj3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.52x10^-5
tremors	1 supporting dataset	Foxj3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.92x10^-5
abnormal skin coloration	1 supporting dataset	Foxj3^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.73x10^-9
preweaning lethality, complete penetrance	1 supporting dataset	Foxj3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal coat appearance	1 supporting dataset	Foxj3^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	8.85x10^-6
unresponsive to tactile stimuli	1 supporting dataset	Foxj3^{tm1b(EUCOMM)Wtsi}	heterozygote	E18.5	N/A ^*
increased bone mineral content	1 supporting dataset	Foxj3^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.35x10^-5
increased circulating calcium level	1 supporting dataset	Foxj3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.9x10^-6
abnormal eye morphology	1 supporting dataset	Foxj3^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
abnormal coat/ hair morphology	1 supporting dataset	Foxj3^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.43x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Foxj3.

Associated images

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Histopathology

There is no histopathology data found for Foxj3.

IMPC related publications

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External links

No external links available for Foxj3.

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*Foxj3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Foxj3^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Foxj3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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