Rps6kc1 | ribosomal protein S6 kinase polypeptide 1

GeneMGI:2443419Synonyms: RPK118, B130003F20Rik

Physiological systems

14 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Nervous system Vision/eye

12 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	1 supporting dataset	Rps6kc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.09x10^-5
abnormal eye anterior chamber depth	1 supporting dataset	Rps6kc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.48x10^-5
abnormal retina outer nuclear layer morphology	1 supporting dataset	Rps6kc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.2x10^-5
decreased total retina thickness	1 supporting dataset	Rps6kc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.22x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rps6kc1.

Associated images

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Histopathology

There is no histopathology data found for Rps6kc1.

IMPC related publications

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External links

No external links available for Rps6kc1.

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*Rps6kc1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rps6kc1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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