Tmem74 | transmembrane protein 74

GeneMGI:2443417Synonyms: B230382K22Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Hematopoietic system Renal/urinary system

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal epididymis morphology	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
small thymus	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal ovary morphology	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged spleen	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Tmem74^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem74.

Associated images

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Histopathology

There is no histopathology data found for Tmem74.

IMPC related publications

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External links

No external links available for Tmem74.

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*Tmem74^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Tmem74^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tmem74^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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