Fndc9 | fibronectin type III domain containing 9

GeneMGI:2443410Synonyms: C030019I05Rik

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean platelet volume	1 supporting dataset	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.55x10^-6
increased total body fat amount	2 supporting datasets	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.29x10^-10
female infertility	1 supporting dataset	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased thigmotaxis	1 supporting dataset	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.63x10^-5
decreased lean body mass	2 supporting datasets	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.08x10^-8
decreased bone mineral content	1 supporting dataset	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.58x10^-5
hyperactivity	6 supporting datasets	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.75x10^-20
decreased grip strength	2 supporting datasets	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.21x10^-6
increased circulating bilirubin level	1 supporting dataset	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.04x10^-9
increased circulating alkaline phosphatase level	1 supporting dataset	Fndc9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.89x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fndc9.

Associated images

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Histopathology

There is no histopathology data found for Fndc9.

IMPC related publications

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External links

No external links available for Fndc9.

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*Fndc9^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Fndc9^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Fndc9^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fndc9^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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