Brinp2 | bone morphogenic protein/retinoic acid inducible neural-specific 2

GeneMGI:2443333Synonyms: 6430517E21Rik, Fam5b

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Cardiovascular system

17 No significant impact

5 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased heart rate1 supporting datasetBrinp2em1(IMPC)WtsihomozygoteEarly adult3.38x10-5 
abnormal gait1 supporting datasetBrinp2em1(IMPC)WtsihomozygoteEarly adult1.41x10-7 
hyperactivity1 supporting datasetBrinp2em1(IMPC)WtsihomozygoteEarly adult6.59x10-5 
abnormal vocalization1 supporting datasetBrinp2em1(IMPC)WtsihomozygoteEarly adult8x10-7 
prolonged RR interval1 supporting datasetBrinp2em1(IMPC)WtsihomozygoteEarly adult7.93x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Brinp2em1(IMPC)WtsiExon Deletionmouse
Brinp2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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