Fa2h | fatty acid 2-hydroxylase

GeneMGI:2443327Synonyms: Faxdc1, G630055L08Rik

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system

10 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal skin morphology	2 supporting datasets	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased circulating HDL cholesterol level	1 supporting dataset	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	9.09x10^-5
abnormal coat/ hair morphology	3 supporting datasets	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	6.83x10^-18
abnormal vitreous body morphology	1 supporting dataset	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	6.27x10^-8
decreased circulating cholesterol level	1 supporting dataset	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	1.59x10^-6
abnormal testis morphology	1 supporting dataset	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased freezing behavior	1 supporting dataset	Fa2h^em1(IMPC)Mbp	homozygote	Early adult	4.27x10^-23

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fa2h.

Associated images

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Histopathology

There is no histopathology data found for Fa2h.

IMPC related publications

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External links

No external links available for Fa2h.

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*Fa2h^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Fa2h^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fa2h^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Fa2h^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fa2h^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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