Fbxw16 | F-box and WD-40 domain protein 16
Physiological systems
21 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Craniofacial Mortality/aging
13 No significant impact
3 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal thymus morphology | 2 supporting datasets | Fbxw16em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal uterus morphology | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| enlarged thymus | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| small thymus | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| increased CD8-positive, naive alpha-beta T cell number | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | heterozygote | Early adult | 5.29x10-6 | ||
| abnormal spleen morphology | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal tooth morphology | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Fbxw16em1(IMPC)Ccpcz | homozygote | E9.5 | N/A * |
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External links
No external links available for Fbxw16.
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| Fbxw16em1(IMPC)Ccpcz | Exon Deletion | | mouse |