Mindy2 | MINDY lysine 48 deubiquitinase 2

GeneMGI:2443086Synonyms: B230380D07Rik, Fam63b

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Skeleton Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount1 supporting datasetMindy2em1(IMPC)HhomozygoteEarly adult5.12x10-5 
decreased lean body mass1 supporting datasetMindy2em1(IMPC)HhomozygoteEarly adult4.48x10-5 
increased bone mineral content1 supporting datasetMindy2em1(IMPC)HhomozygoteEarly adult1.43x10-5 
prolonged RR interval1 supporting datasetMindy2em1(IMPC)HhomozygoteEarly adult2.74x10-8 
decreased heart rate1 supporting datasetMindy2em1(IMPC)HhomozygoteEarly adult8.37x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mindy2em1(IMPC)HExon Deletionmouse
Mindy2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Mindy2tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Mindy2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Mindy2tm2e(KOMP)WtsiTargeted, non-conditional allelees cell

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