Tns3 | tensin 3

GeneMGI:2443012Synonyms: Tens1, F830010I22Rik, +1 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Muscle Skeleton Mortality/aging Cardiovascular system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased cardiac muscle contractility	2 supporting datasets	Tns3^em1(IMPC)Bay	heterozygote	Late adult	2.16x10^-5
increased fasting circulating glucose level	1 supporting dataset	Tns3^em1(IMPC)Bay	heterozygote	Late adult	5.38x10^-5
preweaning lethality, incomplete penetrance	3 supporting datasets	Tns3^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Tns3^em1(IMPC)Bay	heterozygote	Late adult	6.47x10^-5
abnormal head morphology	1 supporting dataset	Tns3^em1(IMPC)Bay	heterozygote	Early adult	4.03x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tns3.

Associated images

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Histopathology

There is no histopathology data found for Tns3.

IMPC related publications

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External links

No external links available for Tns3.

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*Tns3^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Tns3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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